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Compositions and methods for siRNA inhibition of I

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专利名称:Compositions and methods for siRNA

inhibition of ICAM-1

发明人:Samuel J. Reich,Michael J. Tolentino申请号:US12329221申请日:20081205公开号:US07847090B2公开日:20101207

专利附图:

摘要:RNA interference using small interfering RNAs which are specific for the ICAM-1gene inhibits expression of this gene. Diseases which involve ICAM-1-mediated celladhesion, such as inflammatory and autoimmune diseases, diabetic retinopathy and other

complications arising from type I diabetes, age related macular degeneration and manytypes of cancer, can be treated by administering the small interfering RNAs.

申请人:Samuel J. Reich,Michael J. Tolentino

地址:Miami Beach FL US,Lakeland FL US

国籍:US,US

代理机构:Pepper Hamilton LLP

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