专利名称：Improved mutants of (2,5-dkg) reductase发明人：POWERS DAVID B,ANDERSON STEPHEN申请号：AU1691197申请日：19970109公开号：AU1691197A公开日：19970801
摘要：Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the followingcharacteristics: improved temperature stability, increased resistance to substrateinhibition, increased turnover of the substrate by the enzyme and increased affinity forthe substrate.
申请人：UNIV RUTGERS
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