Antimalaria vaccines

专利名称：Antimalaria vaccines发明人：Certa, Ulrich, Dr.申请号：EP88114016.4申请日：19880827公开号：EP0309746A1公开日：190405

专利附图：

摘要： The invention relates to polypeptides which share at least one epitope specificto a Plasmodium falciparum Merozoitenantigen having a molecular weight of about41,000 daltons, and a process for their preparation. Further, the invention immunogeniccompositions containing such a polypeptide and a suitable adjuvant, a DNA sequence

encoding such a polypeptide, replicable microbial vectors containing such DNA sequence,microorganisms containing such replicable vector, as well as antibodies against relates toa polypeptide of the invention. Further, the invention provides methods for thepreparation of the immunogenic compositions of the microorganism and the antibody,and the use of the polypeptides and immunogenic composition for the immunization ofmammals against malaria relates.

申请人：F. HOFFMANN-LA ROCHE AG

地址：Postfach 3255 4002 Basel CH

国籍：CH

代理机构：Mezger, Wolfgang, Dr.

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